Markets: JITA · AMARR · DODIXIE · RENS
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Arbitrage in EVE Online is buying an item cheaply in one trade hub and selling it higher in another. Between Jita, Amarr, Dodixie and Rens the same item routinely differs in price by more than it costs to move it — that difference, minus hauling and fees, is the trade.
The figure most calculators show is fiction, because they price an entire cargo hold at the single best order on each side. You cannot buy a thousand units at the best price — you eat through the order book and the price climbs as you go. This page walks the real depth on both sides, so profit per run is what you would actually clear, not what the top of the book suggests.
Cargo volume decides how much fits in one run; daily volume decides how fast the destination absorbs it — dumping a week of supply at once moves the price against you. Hauling between hubs also carries a risk no calculator can price: valuable cargo in a slow ship is a target.
Want the long version — picking routes, sizing a run to the ship you actually fly, and staying alive on the way? Read the EVE Online arbitrage guide.